Biological Approaches to Spinal Disc Repair and Regeneration for Clinicians

Biological Approaches to Spinal Disc Repair and Regeneration for Clinicians

Roger Hartl

Larry Bonassar

ISBN 9781626232501
Godina Izdanja 2017
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Although there have been significant advancements in minimally invasive spinal surgery techniques in the last few decades, optimal outcomes for chronic low back pain remain elusive. A number of promising clinical trials have been conducted using tissue engineering and biological interventions for disc degeneration. Written by renowned innovators, this is the first book that covers implementation of these groundbreaking approaches for disc disease. The text begins with key fundamentals including anatomy and physiology, pathophysiology, imaging and biomechanics to delineate healthy versus diseased spine. Subsequent sections discuss treatment strategies, research findings, and future developments. Throughout each chapter, renowned spine surgeons and scientists share clinical pearls gleaned from hands-on experience. Key Highlights: * The current state of the art in biological and tissue engineering procedures for spinal disorders. * Treatment methodologies including nucleus replacement and repair, annulus fibrosus repair, total disc transplantation, and mechanical total disc replacementInnovative treatment strategies for disc regeneration, such as genes and proteins. * Growth factors including platelet-rich plasma (PRP), which has shown promise for the stimulation and acceleration of bone and soft tissue healing. * Cell-based therapy for spinal disc regeneration and repair including the use of stem cells and chondrocytesIn-depth discussion of research including animal versus human model, in-vitro, and a summary of biologic clinical trials. This is a must-have resource for trainee and practicing orthopaedic surgeons and neurosurgeons who treat patients for spine-related conditions. It is essential reading for all clinicians who have an interest in cutting-edge tissue engineering and biological treatment interventions.

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Autor Roger Hartl, Larry Bonassar
ISBN 9781626232501
EAN 1626232504
Godina izdanja 2017
Izdavač Thieme
Broj stranica 216
Format i dimenzije 216 x 279mm, tvrd povez